Primary aldosteronism, diagnosed by the aldosterone to renin ratio, is a common cause of hypertension.

نویسندگان

  • Pitt O Lim
  • Thomas M MacDonald
چکیده

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Diagnostic value of the post-captopril test in primary aldosteronism.

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Primary hyperaldosteronism is one of the few causes of hypertension that can be cured by surgery. Primary hyperaldosteronism is caused by adrenocortical adenoma or hyperplasia. It is important to differentiate between adrenal adenoma and hyperplasia because the preferred treatments are different. In all patients with new-onest or worsening hypertension the primary hyperaldosteronism should be c...

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Evolution of diagnostic criteria for primary aldosteronism: why is it more common in "drug-resistant" hypertension today?

The recent "epidemic" of primary aldosteronism reported in the literature is most likely related to the widespread acceptance that with easy access to accurate measurements of renin and aldosterone, it is no longer necessary to wait until hypokalemia has become profound before embarking on diagnostic testing to attempt to ferret out this most common cause of "essential" hypertension. This is es...

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Should all Hypertensive Patients be Screened for Primary Aldosteronism?

Primary Aldosteronism (PA) is defined as non-suppressible hyper secretion of aldosterone by adrenal glands, with consequent suppression of plasma renin activity. It was described by Jerome Conn in 1955 [1]. It is said to be an under diagnosed and important secondary endocrine cause of hypertension, and is one of the few potentially curable causes of hypertension using both medical and surgical ...

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Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio.

BACKGROUND The value of the ratio of plasma aldosterone concentration (aldosterone) to plasma renin activity (renin) to identify patients at risk for primary aldosteronism is controversial. We determined the sensitivity, specificity, and predictive value of the ratio to identify combinations of renin and aldosterone compatible with primary aldosteronism. METHODS The ratio was calculated in 50...

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عنوان ژورنال:
  • Clinical endocrinology

دوره 59 4  شماره 

صفحات  -

تاریخ انتشار 2003